Glutamate: What It Is & Function - Cleveland Clinic
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Glutamate is also needed for making another neurotransmitter in your brain called gamma-aminobutyric acid (GABA). GABA is known as the “calming” neurotransmitter. It’s involved in sleep, relaxation, anxiety regulation and muscle function. Glutamate is also an amino acid. Amino acids are the building blocks of protein.
Stiff Person Syndrome (SPS): What It Is, Symptoms & Treatment
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Many people with stiff person syndrome make antibodies against glutamic acid decarboxylase (GAD). GAD makes a neurotransmitter called gamma-aminobutyric acid (GABA), which helps control muscle movement. Researchers don’t yet understand the exact role that GAD plays in the development and worsening of stiff person syndrome.