Dihydropyridines primarily relax blood vessels and are mainly used to lower blood pressure. They have little effect on heart rate. Examples include amlodipine, nifedipine, and felodipine. Non-dihydropyridines act on both blood vessels and the heart.

Compared with certain other L -type calcium channel blockers (for example those of the phenylalkylamine class such as verapamil) that have significant action at the heart, the dihydropyridine calcium channel blockers lower blood pressure mainly by relaxing the smooth muscle of the blood vessel walls. [3]

Calciumkanalblocker (CCBs) sind eine Klasse von Medikamenten, die spannungsabhängige Calciumkanäle vom L-Typ der glatten Muskelzellen des Herzens und der Gefäße hemmen. Die Hemmung dieser Kanäle führt zu Vasodilatation und Kardiodepression.

Early trials of dihydropyridine calcium channel blockers (DCCBs) suggest a detrimental effect on intraglomerular pressure and an association with albuminuria.

Ausführliche Informationen finden Sie unter den Arzneimittelgruppen und Wirkstoffen: Dihydropyridine: Phenylalkylamine: Benzothiazepine: Antivertiginosa: Interessenkonflikte: Keine / unabhängig. Der Autor hat keine Beziehungen zu den Herstellern und ist nicht am Verkauf der erwähnten Produkte beteiligt.

Dihydropyridine (DHP) calcium channel blockers are derived from the molecule dihydropyridine and often used to reduce systemic vascular resistance and arterial pressure.

Blodtryksmedicinen dihydropyridin-calciumkanalblokkere (DCCB) var koblet med større risiko for alvorlige nyreudfald hos personer med type 2-diabetes og diabetisk nyresygdom, selv om personerne samtidig fik RAS- og SGLT2-hæmmere.

Dihydropyridine calcium-channel blockers (DCCBs) work by relaxing blood vessels, and are frequently used as second-line therapies in people with diabetic kidney disease (DKD), researchers said. Examples include amlodipine, nifedipine, and felodipine.

Learn how these blood pressure medicines open the arteries, help ease chest pain and treat an irregular heartbeat.

Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.